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Specialization of the chromatin remodeler RSC to mobilize partially-unwrapped nucleosomes

SWI/SNF-family chromatin remodeling complexes, such as S. cerevisiae RSC, slide and eject nucleosomes to regulate transcription. Within nucleosomes, stiff DNA sequences confer spontaneous partial unwrapping, prompting whether and how SWI/SNF-family remodelers are specialized to remodel partially-unw...

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Detalles Bibliográficos
Autores principales: Schlichter, Alisha, Kasten, Margaret M, Parnell, Timothy J, Cairns, Bradley R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308085/
https://www.ncbi.nlm.nih.gov/pubmed/32496195
http://dx.doi.org/10.7554/eLife.58130