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Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo

PURPOSE: Acute myeloid leukemia (AML) is a complex malignancy characterized by the clonal expansion of immature myeloid precursors. The standard treatment for newly diagnosed AML is chemotherapy consisting of cytosine arabinoside (Ara-C) and anthracyclines with disappointing clinical outcomes and se...

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Detalles Bibliográficos
Autores principales: Wu, Hongzhang, Cheng, Xurui, Huang, Feiyan, Shao, Gang, Meng, Yueming, Wang, Lingfei, Wang, Tao, Jia, Xiaoyuan, Yang, Tianxin, Wang, Xi, Fu, Caiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308242/
https://www.ncbi.nlm.nih.gov/pubmed/32606608
http://dx.doi.org/10.2147/DDDT.S244648