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Aprepitant Sensitizes Acute Myeloid Leukemia Cells to the Cytotoxic Effects of Cytosine Arabinoside in vitro and in vivo
PURPOSE: Acute myeloid leukemia (AML) is a complex malignancy characterized by the clonal expansion of immature myeloid precursors. The standard treatment for newly diagnosed AML is chemotherapy consisting of cytosine arabinoside (Ara-C) and anthracyclines with disappointing clinical outcomes and se...
Autores principales: | Wu, Hongzhang, Cheng, Xurui, Huang, Feiyan, Shao, Gang, Meng, Yueming, Wang, Lingfei, Wang, Tao, Jia, Xiaoyuan, Yang, Tianxin, Wang, Xi, Fu, Caiyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308242/ https://www.ncbi.nlm.nih.gov/pubmed/32606608 http://dx.doi.org/10.2147/DDDT.S244648 |
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