NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis

DNA double-strand breaks (DSBs) pose a serious threat to genomic stability. Paradoxically, hundreds of programed DSBs are generated by SPO11 in meiotic prophase, which are exclusively repaired by homologous recombination (HR) to promote obligate crossover between homologous chromosomes. In somatic c...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Tang, Zhenghui, Li, Lejun, Lu, Lin-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308329/
https://www.ncbi.nlm.nih.gov/pubmed/31965061
http://dx.doi.org/10.1038/s41418-020-0493-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308329/
https://www.ncbi.nlm.nih.gov/pubmed/31965061
http://dx.doi.org/10.1038/s41418-020-0493-4

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