Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons

Vps35 (vacuolar protein sorting 35) is a key component of retromer that regulates transmembrane protein trafficking. Dysfunctional Vps35 is a risk factor for neurodegenerative diseases, including Parkinson’s and Alzheimer’s diseases. Vps35 is highly expressed in developing pyramidal neurons, and its...

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Detalles Bibliográficos
Autores principales: Tang, Fu-Lei, Zhao, Lu, Zhao, Yang, Sun, Dong, Zhu, Xiao-Juan, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308361/
https://www.ncbi.nlm.nih.gov/pubmed/31907392
http://dx.doi.org/10.1038/s41418-019-0487-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308361/
https://www.ncbi.nlm.nih.gov/pubmed/31907392
http://dx.doi.org/10.1038/s41418-019-0487-2

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