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Uncovering the PIDDosome and caspase-2 as regulators of organogenesis and cellular differentiation
The PIDDosome is a multiprotein complex that drives activation of caspase-2, an endopeptidase originally implicated in apoptosis. Yet, unlike other caspases involved in cell death and inflammation, caspase-2 seems to exert additional versatile functions unrelated to cell death. These emerging roles...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308375/ https://www.ncbi.nlm.nih.gov/pubmed/32415279 http://dx.doi.org/10.1038/s41418-020-0556-6 |