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An entropy-based metric for assessing the purity of single cell populations

Single-cell RNA sequencing (scRNA-seq) is a versatile tool for discovering and annotating cell types and states, but the determination and annotation of cell subtypes is often subjective and arbitrary. Often, it is not even clear whether a given cluster is uniform. Here we present an entropy-based s...

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Detalles Bibliográficos
Autores principales: Liu, Baolin, Li, Chenwei, Li, Ziyi, Wang, Dongfang, Ren, Xianwen, Zhang, Zemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308400/
https://www.ncbi.nlm.nih.gov/pubmed/32572028
http://dx.doi.org/10.1038/s41467-020-16904-3