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Agrin-Mediated Cardiac Regeneration: Some Open Questions

After cardiac injury, the mammalian adult heart has a very limited capacity to regenerate, due to the inability of fully differentiated cardiomyocytes (CMs) to efficiently proliferate. This has been directly linked to the extracellular matrix (ECM) surrounding and connecting cardiomyocytes, as its i...

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Detalles Bibliográficos
Autores principales: Bigotti, Maria Giulia, Skeffington, Katie L., Jones, Ffion P., Caputo, Massimo, Brancaccio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308530/
https://www.ncbi.nlm.nih.gov/pubmed/32612983
http://dx.doi.org/10.3389/fbioe.2020.00594