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COVID-19 as a viral functional ACE2 deficiency disorder with ACE2 related multi-organ disease

SARS-CoV-2, the agent of COVID-19, shares a lineage with SARS-CoV-1, and a common fatal pulmonary profile but with striking differences in presentation, clinical course, and response to treatment. In contrast to SARS-CoV-1 (SARS), COVID-19 has presented as an often bi-phasic, multi-organ pathology,...

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Detalles Bibliográficos
Autores principales: Gan, Rosemary, Rosoman, Nicholas P., Henshaw, David J.E., Noble, Euan P., Georgius, Peter, Sommerfeld, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7308773/
https://www.ncbi.nlm.nih.gov/pubmed/32758871
http://dx.doi.org/10.1016/j.mehy.2020.110024