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Fiber Optic Particle Plasmon Resonance Biosensor for Label-Free Detection of Nucleic Acids and Its Application to HLA-B27 mRNA Detection in Patients with Ankylosing Spondylitis

We developed a label-free, real-time, and highly sensitive nucleic acid biosensor based on fiber optic particle plasmon resonance (FOPPR). The biosensor employs a single-strand deoxyoligonucleotides (ssDNA) probe, conjugated to immobilized gold nanoparticles on the core surface of an optical fiber....

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Detalles Bibliográficos
Autores principales: Tseng, Yen-Ta, Li, Wan-Yun, Yu, Ya-Wen, Chiang, Chang-Yue, Liu, Su-Qin, Chau, Lai-Kwan, Lai, Ning-Sheng, Chou, Cheng-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309088/
https://www.ncbi.nlm.nih.gov/pubmed/32492975
http://dx.doi.org/10.3390/s20113137