Continuous Online Protein Quality Monitoring during Perfusion Culture Production Using an Integrated Micro/Nanofluidic System

[Image: see text] We demonstrate a new micro/nanofluidic system for continuous and automatic monitoring of protein product size and quantity directly from the culture supernatant during a high-cell-concentration CHO cell perfusion culture. A microfluidic device enables clog-free cell retention for a...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Taehong, Ko, Sung Hee, Hamel, Jean-François P., Han, Jongyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309224/
https://www.ncbi.nlm.nih.gov/pubmed/32167286
http://dx.doi.org/10.1021/acs.analchem.9b05835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309224/
https://www.ncbi.nlm.nih.gov/pubmed/32167286
http://dx.doi.org/10.1021/acs.analchem.9b05835

Ejemplares similares