Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: (18)F-AZD9272

[Image: see text] The metabotropic glutamate receptor subtype mGluR5 has been proposed as a potential drug target for CNS disorders such as anxiety, depression, Parkinson’s disease, and epilepsy. The AstraZeneca compound AZD9272 has previously been labeled with carbon-11 and used as a PET radioligan...

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Detalles Bibliográficos
Autores principales: Nag, Sangram, Varnäs, Katarina, Arakawa, Ryosuke, Jahan, Mahabuba, Schou, Magnus, Farde, Lars, Halldin, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309225/
https://www.ncbi.nlm.nih.gov/pubmed/32167745
http://dx.doi.org/10.1021/acschemneuro.9b00680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309225/
https://www.ncbi.nlm.nih.gov/pubmed/32167745
http://dx.doi.org/10.1021/acschemneuro.9b00680

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