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Potential G-Quadruplex Forming Sequences and N(6)-Methyladenosine Colocalize at Human Pre-mRNA Intron Splice Sites

[Image: see text] Maturation of mRNA in humans involves modifying the 5′ and 3′ ends, splicing introns, and installing epitranscriptomic modifications that are essential for mRNA biogenesis. With respect to epitranscriptomic modifications, they are usually installed in specific consensus motifs, alt...

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Detalles Bibliográficos
Autores principales: Jara-Espejo, Manuel, Fleming, Aaron M., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309266/
https://www.ncbi.nlm.nih.gov/pubmed/32396327
http://dx.doi.org/10.1021/acschembio.0c00260