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A Whole Genome-Wide Arrayed CRISPR Screen in Primary Organ Fibroblasts to Identify Regulators of Kidney Fibrosis

Kidney fibrosis presents a hallmark of chronic kidney disease. With ever-increasing patient numbers and limited treatment options available, novel strategies for therapeutic intervention in kidney disease are warranted. Fibrosis commonly results from a wound healing response to repeated or chronic t...

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Detalles Bibliográficos
Autores principales: Turner, Robert J., Golz, Stefan, Wollnik, Carina, Burkhardt, Nils, Sternberger, Ina, Andag, Uwe, Cornils, Hauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309357/
https://www.ncbi.nlm.nih.gov/pubmed/32425084
http://dx.doi.org/10.1177/2472555220915851