An Economical Route to Lamivudine Featuring a Novel Strategy for Stereospecific Assembly

[Image: see text] An economical synthesis of lamivudine was developed by employing a new method to establish the stereochemistry about the heterocyclic oxathiolane ring. Toward this end, an inexpensive and readily accessible lactic acid derivative served the dual purpose of activating the carbohydra...

Descripción completa

Detalles Bibliográficos
Autores principales: Snead, David R., McQuade, D. Tyler, Ahmad, Saeed, Krack, Rudy, Stringham, Rodger W., Burns, Justina M., Abdiaj, Irini, Gopalsamuthiram, Vijayagopal, Nelson, Ryan C., Gupton, B. Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309434/
https://www.ncbi.nlm.nih.gov/pubmed/32587454
http://dx.doi.org/10.1021/acs.oprd.0c00083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309434/
https://www.ncbi.nlm.nih.gov/pubmed/32587454
http://dx.doi.org/10.1021/acs.oprd.0c00083

Ejemplares similares