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An Economical Route to Lamivudine Featuring a Novel Strategy for Stereospecific Assembly
[Image: see text] An economical synthesis of lamivudine was developed by employing a new method to establish the stereochemistry about the heterocyclic oxathiolane ring. Toward this end, an inexpensive and readily accessible lactic acid derivative served the dual purpose of activating the carbohydra...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309434/ https://www.ncbi.nlm.nih.gov/pubmed/32587454 http://dx.doi.org/10.1021/acs.oprd.0c00083 |