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A Bivalent Human Adenovirus Type 5 Vaccine Expressing the Rabies Virus Glycoprotein and Canine Distemper Virus Hemagglutinin Protein Confers Protective Immunity in Mice and Foxes

The development of a safe and efficient multivalent vaccine has great prospects for application. Both rabies virus (RABV) and canine distemper virus (CDV) are highly infectious antigens, causing lethal diseases in domestic dogs and other carnivores worldwide. In this study, a replication-deficient h...

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Detalles Bibliográficos
Autores principales: Yan, Lina, Zhao, Zhongxin, Xue, Xianghong, Zheng, Wenwen, Xu, Tong, Liu, Lele, Tian, Li, Wang, Xianwei, He, Hongbin, Zheng, Xuexing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309451/
https://www.ncbi.nlm.nih.gov/pubmed/32612580
http://dx.doi.org/10.3389/fmicb.2020.01070