Heat shock protein 47 promotes tumor survival and therapy resistance by modulating AKT signaling via PHLPP1 in colorectal cancer

Objective: Heat shock protein 47 (HSP47) is a collagen-specific molecular chaperone that facilitates collagen maturation. Its role in cancer remains largely unknown. In this study, we investigated the roles of HSP47 in colorectal cancer (CRC) and therapy resistance. Methods: Expression of HSP47 in C...

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Detalles Bibliográficos
Autores principales: Chern, Yijye, Zhang, Peter, Ju, Hyelim, Tai, Isabella T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309463/
https://www.ncbi.nlm.nih.gov/pubmed/32587773
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309463/
https://www.ncbi.nlm.nih.gov/pubmed/32587773
http://dx.doi.org/10.20892/j.issn.2095-3941.2019.0261

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