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Serum antibodies to phosphatidylcholine in MS

OBJECTIVE: To evaluate the value of serum immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies reactive with phosphatidylcholine (PC) and lactosylceramide (LC) as biomarkers in MS. METHODS: We developed an ultrasensitive ELISA technique to analyze serum IgG and IgM antibodies to LC and PC, w...

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Detalles Bibliográficos
Autores principales: Sádaba, Maria Cruz, Rothhammer, Veit, Muñoz, Úrsula, Sebal, Cristina, Escudero, Esther, Kivisäkk, Pia, Garcia Sanchez, Maria Isabel, Izquierdo, Guillermo, Hauser, Stephen L., Baranzini, Sergio E., Oksenberg, Jorge R., Álvarez-Lafuente, Roberto, Bakshi, Rohit, Weiner, Howard L., Quintana, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309529/
https://www.ncbi.nlm.nih.gov/pubmed/32518205
http://dx.doi.org/10.1212/NXI.0000000000000765