Cargando…

Cadmium induces mitophagy via AMP‐activated protein kinases activation in a PINK1/Parkin‐dependent manner in PC12 cells

OBJECTIVES: Cadmium (Cd) induces mitophagy in neuronal cells, but the underlying mechanisms remain unknown. In this study, we aimed to investigate these mechanisms. MATERIALS AND METHODS: The effects of Cd on the mitophagy in rat pheochromocytoma PC12 cells were detected, and the role of PINK1/Parki...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tao, Zhu, Qiaoping, Cao, Binbin, Yuan, Yan, Wen, Shuangquan, Liu, Zongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7309594/
https://www.ncbi.nlm.nih.gov/pubmed/32396704
http://dx.doi.org/10.1111/cpr.12817