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Improving the evaluation of COPD exacerbation treatment effects by accounting for early treatment discontinuations: a post-hoc analysis of randomized clinical trials

BACKGROUND: Chronic obstructive pulmonary disease (COPD) clinical trials aimed at evaluating treatment effects on exacerbations often suffer from early discontinuations of randomized treatment. Treatment discontinuations imply a loss of information and should ideally be considered in the statistical...

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Detalles Bibliográficos
Autores principales: Król, Agnieszka, Palmér, Robert, Rondeau, Virginie, Rennard, Stephen, Eriksson, Ulf G., Jauhiainen, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310001/
https://www.ncbi.nlm.nih.gov/pubmed/32571311
http://dx.doi.org/10.1186/s12931-020-01419-8