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A Novel Next-Generation Sequencing and Analysis Platform to Assess the Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA Extracts

Recombinant adeno-associated virus (rAAV) vectors are increasingly popular gene delivery tools in biological systems. They are safe and lead to high-level, long-term transgene expression. rAAV are available in multiple serotypes, natural or engineered, which enable targeting to a wide array of tissu...

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Detalles Bibliográficos
Autores principales: Guerin, Karen, Rego, Meghan, Bourges, Daniela, Ersing, Ina, Haery, Leila, Harten DeMaio, Kate, Sanders, Erin, Tasissa, Meron, Kostman, Maya, Tillgren, Michelle, Makana Hanley, Luke, Mueller, Isabelle, Mitsopoulos, Alanna, Fan, Melina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310222/
https://www.ncbi.nlm.nih.gov/pubmed/32159396
http://dx.doi.org/10.1089/hum.2019.277