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A Novel Next-Generation Sequencing and Analysis Platform to Assess the Identity of Recombinant Adeno-Associated Viral Preparations from Viral DNA Extracts
Recombinant adeno-associated virus (rAAV) vectors are increasingly popular gene delivery tools in biological systems. They are safe and lead to high-level, long-term transgene expression. rAAV are available in multiple serotypes, natural or engineered, which enable targeting to a wide array of tissu...
Autores principales: | Guerin, Karen, Rego, Meghan, Bourges, Daniela, Ersing, Ina, Haery, Leila, Harten DeMaio, Kate, Sanders, Erin, Tasissa, Meron, Kostman, Maya, Tillgren, Michelle, Makana Hanley, Luke, Mueller, Isabelle, Mitsopoulos, Alanna, Fan, Melina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310222/ https://www.ncbi.nlm.nih.gov/pubmed/32159396 http://dx.doi.org/10.1089/hum.2019.277 |
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