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DNA vaccine encoding heat shock protein 90 protects from murine lupus

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the presence of autoantibodies to multiple self-antigens, including heat shock proteins (HSP). Because of the increased expression of HSP90 and abnormal immune responses to it in SLE, we investigated whet...

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Detalles Bibliográficos
Autores principales: Liu, Aijing, Shi, Fu-Dong, Cohen, Irun R., Castaldo, Giuseppe, Matarese, Giuseppe, Quintana, Francisco J., La Cava, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310240/
https://www.ncbi.nlm.nih.gov/pubmed/32571400
http://dx.doi.org/10.1186/s13075-020-02246-4