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Amplification of KRAS and its heterogeneity in non-Asian gastric adenocarcinomas

BACKGROUND: Gastric cancer is one of the deadliest cancer entities worldwide. While surgery is the only curative treatment option in early tumors, for locally advanced and metastatic patients further therapeutic targets are needed. Several studies not only reported mutations but also amplifications...

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Detalles Bibliográficos
Autores principales: Rehkaemper, Jan, Korenkov, Michael, Quaas, Alexander, Rueschoff, Josef, Pamuk, Aylin, Zander, Thomas, Hillmer, Axel M., Buettner, Reinhard, Hoelscher, Arnulf Heinrich, Bruns, Christiane Josephine, Loeser, Heike, Alakus, Hakan, Schoemig-Markiefka, Birgid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310377/
https://www.ncbi.nlm.nih.gov/pubmed/32571252
http://dx.doi.org/10.1186/s12885-020-06996-x