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Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells

BACKGROUND: The transmembrane glycoprotein podoplanin (PDPN) is upregulated in some tumors and has gained attention as a malignant tumor biomarker. PDPN molecules have platelet aggregation-stimulating domains and, are therefore, suggested to play a role in tumor-induced platelet activation, which in...

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Detalles Bibliográficos
Autores principales: Watanabe, Nobuo, Kidokoro, Masako, Tanaka, Makiko, Inoue, Shigeaki, Tsuji, Tomoatsu, Akatuska, Hisako, Okada, Chisa, Iida, Yumi, Okada, Yoshinori, Suzuki, Yusuke, Sato, Takehito, Yahata, Takashi, Hirayama, Noriaki, Nakagawa, Yoshihide, Inokuchi, Sadaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310449/
https://www.ncbi.nlm.nih.gov/pubmed/32581653
http://dx.doi.org/10.1186/s12935-020-01328-2