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Podoplanin is indispensable for cell motility and platelet-induced epithelial-to-mesenchymal transition-related gene expression in esophagus squamous carcinoma TE11A cells
BACKGROUND: The transmembrane glycoprotein podoplanin (PDPN) is upregulated in some tumors and has gained attention as a malignant tumor biomarker. PDPN molecules have platelet aggregation-stimulating domains and, are therefore, suggested to play a role in tumor-induced platelet activation, which in...
Autores principales: | Watanabe, Nobuo, Kidokoro, Masako, Tanaka, Makiko, Inoue, Shigeaki, Tsuji, Tomoatsu, Akatuska, Hisako, Okada, Chisa, Iida, Yumi, Okada, Yoshinori, Suzuki, Yusuke, Sato, Takehito, Yahata, Takashi, Hirayama, Noriaki, Nakagawa, Yoshihide, Inokuchi, Sadaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310449/ https://www.ncbi.nlm.nih.gov/pubmed/32581653 http://dx.doi.org/10.1186/s12935-020-01328-2 |
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