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Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells
BACKGROUND: Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased phosphorylation of essential effectors such as Smoothened (SM...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310537/ https://www.ncbi.nlm.nih.gov/pubmed/32576205 http://dx.doi.org/10.1186/s12964-020-00591-0 |