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Phosphoproteomics of short-term hedgehog signaling in human medulloblastoma cells

BACKGROUND: Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased phosphorylation of essential effectors such as Smoothened (SM...

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Detalles Bibliográficos
Autores principales: Scheidt, Tamara, Alka, Oliver, Gonczarowska-Jorge, Humberto, Gruber, Wolfgang, Rathje, Florian, Dell’Aica, Margherita, Rurik, Marc, Kohlbacher, Oliver, Zahedi, René P., Aberger, Fritz, Huber, Christian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310537/
https://www.ncbi.nlm.nih.gov/pubmed/32576205
http://dx.doi.org/10.1186/s12964-020-00591-0