A randomized single-dose, two-period crossover bioequivalence study of two fixed-dose Paracetamol/Orphenadrine combination preparations in healthy volunteers under fasted condition

BACKGROUND: Paracetamol/Orphenadrine is a fixed dose combination containing 35 mg orphenadrine and 450 mg paracetamol. It has analgesic and muscle relaxant properties and is widely available as generics. This study is conducted to investigate the relative bioavailability and bioequivalence between o...

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Detalles Bibliográficos
Autores principales: Cheah, Kit Yee, Mah, Kar Yee, Pang, Lai Hui, Ng, Shi Min, Wong, Jia Woei, Tan, Siew Siew, Tan, Hong Zhe, Yuen, Kah Hay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310552/
https://www.ncbi.nlm.nih.gov/pubmed/32576287
http://dx.doi.org/10.1186/s40360-020-00416-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310552/
https://www.ncbi.nlm.nih.gov/pubmed/32576287
http://dx.doi.org/10.1186/s40360-020-00416-3

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