Mitochondrial ROS accumulation inhibiting JAK2/STAT3 pathway is a critical modulator of CYT997-induced autophagy and apoptosis in gastric cancer

BACKGROUND: Gastric cancer (GC) is a common form of malignant cancer in worldwide which has a poor prognosis. Despite recent improvements in the treatment of GC, the prognosis is not yet satisfactory for GC patients. CYT997, a novel microtubule-targeting agent, recently has been identified to be a p...

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Detalles Bibliográficos
Autores principales: Cao, Ya, Wang, Jinglong, Tian, Hua, Fu, Guo-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310559/
https://www.ncbi.nlm.nih.gov/pubmed/32576206
http://dx.doi.org/10.1186/s13046-020-01621-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310559/
https://www.ncbi.nlm.nih.gov/pubmed/32576206
http://dx.doi.org/10.1186/s13046-020-01621-y

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