FAK signaling in Cancer-Associated Fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication

Cancer-associated fibroblasts (CAFs) are activated fibroblasts that constitute the major components of tumor microenvironment (TME) and play crucial roles in tumor development and metastasis. Here, we generated fibroblast-specific inducible focal adhesion kinase (FAK) knockout (cKO) mice in a breast...

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Detalles Bibliográficos
Autores principales: Wu, Hsin-Jung, Hao, Mingang, Yeo, Syn Kok, Guan, Jun-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310603/
https://www.ncbi.nlm.nih.gov/pubmed/31988451
http://dx.doi.org/10.1038/s41388-020-1162-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310603/
https://www.ncbi.nlm.nih.gov/pubmed/31988451
http://dx.doi.org/10.1038/s41388-020-1162-2

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