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FAK signaling in Cancer-Associated Fibroblasts promotes breast cancer cell migration and metastasis by exosomal miRNAs-mediated intercellular communication

Cancer-associated fibroblasts (CAFs) are activated fibroblasts that constitute the major components of tumor microenvironment (TME) and play crucial roles in tumor development and metastasis. Here, we generated fibroblast-specific inducible focal adhesion kinase (FAK) knockout (cKO) mice in a breast...

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Detalles Bibliográficos
Autores principales:	Wu, Hsin-Jung, Hao, Mingang, Yeo, Syn Kok, Guan, Jun-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310603/ https://www.ncbi.nlm.nih.gov/pubmed/31988451 http://dx.doi.org/10.1038/s41388-020-1162-2

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