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Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1

The transcriptional regulatory machinery in mitochondrial bioenergetics is complex and is still not completely understood. We previously demonstrated that the histone methyltransferase Smyd1 regulates mitochondrial energetics. Here, we identified Perm1 (PPARGC-1 and ESRR-induced regulator, muscle sp...

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Detalles Bibliográficos
Autores principales: Oka, Shin-ichi, Sabry, Amira D., Horiuchi, Amanda K., Cawley, Keiko M., O’Very, Sean A., Zaitsev, Maria A., Shankar, Thirupura S., Byun, Jaemin, Mukai, Risa, Xu, Xiaoyong, Torres, Natalia S., Kumar, Anil, Yazawa, Masayuki, Ling, Jing, Taleb, Iosif, Saijoh, Yukio, Drakos, Stavros G., Sadoshima, Junichi, Warren, Junco S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310723/
https://www.ncbi.nlm.nih.gov/pubmed/32574189
http://dx.doi.org/10.1371/journal.pone.0234913