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ACE2 and TMPRSS2 variation in savanna monkeys (Chlorocebus spp.): Potential risk for zoonotic/anthroponotic transmission of SARS-CoV-2 and a potential model for functional studies

The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has devastated health infrastructure around the world. Both ACE2 (an entry receptor) and TMPRSS2 (used by the virus for spike protein priming) are key proteins to SARS-CoV-2 cell entry, enabling progression to COVID-19 in humans. Comparati...

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Detalles Bibliográficos
Autores principales: Schmitt, Christopher A., Bergey, Christina M., Jasinska, Anna J., Ramensky, Vasily, Burt, Felicity, Svardal, Hannes, Jorgensen, Matthew J., Freimer, Nelson B., Grobler, J. Paul, Turner, Trudy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310727/
https://www.ncbi.nlm.nih.gov/pubmed/32574196
http://dx.doi.org/10.1371/journal.pone.0235106