Antifibrotic role of low-dose mitomycin-c-induced cellular senescence in trabeculectomy models

PURPOSE: We assessed whether mitomycin-C (MMC) has different antifibrotic mechanisms in trabeculectomy wound healing. METHODS: We identified 2 concentrations of MMC as “low-dose” by using WST-1 assay, Lactic dehydrogenase assay, and fluorescence-activated cell sorting flow cytometry. Senescence-asso...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Le-Tien, Chen, Jiann-Torng, Lu, Da-Wen, Tai, Ming-Cheng, Liang, Chang-Min, Chen, Ching-Long, Pao, Shu-I, Hsu, Chih-Kang, Chen, Yi-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310836/
https://www.ncbi.nlm.nih.gov/pubmed/32574191
http://dx.doi.org/10.1371/journal.pone.0234706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310836/
https://www.ncbi.nlm.nih.gov/pubmed/32574191
http://dx.doi.org/10.1371/journal.pone.0234706

Ejemplares similares