Cargando…

Antifibrotic role of low-dose mitomycin-c-induced cellular senescence in trabeculectomy models

PURPOSE: We assessed whether mitomycin-C (MMC) has different antifibrotic mechanisms in trabeculectomy wound healing. METHODS: We identified 2 concentrations of MMC as “low-dose” by using WST-1 assay, Lactic dehydrogenase assay, and fluorescence-activated cell sorting flow cytometry. Senescence-asso...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Le-Tien, Chen, Jiann-Torng, Lu, Da-Wen, Tai, Ming-Cheng, Liang, Chang-Min, Chen, Ching-Long, Pao, Shu-I, Hsu, Chih-Kang, Chen, Yi-Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310836/ https://www.ncbi.nlm.nih.gov/pubmed/32574191 http://dx.doi.org/10.1371/journal.pone.0234706

Ejemplares similares

Comparison of the Outcome of Repeat Trabeculectomy with Adjunctive Mitomycin C and Initial Trabeculectomy
por: Cankaya, Ali Bulent, et al.
Publicado: (2011)

Surgical outcomes of repeat trabeculectomy augmented with high dose mitomycin C
por: Rajendrababu, Sharmila, et al.
Publicado: (2019)

Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial–mesenchymal transition in proliferative vitreoretinopathy
por: Pao, Shu-I, et al.
Publicado: (2021)

MicroRNA-4516 suppresses proliferative vitreoretinopathy development via negatively regulating OTX1
por: Pao, Shu-I, et al.
Publicado: (2022)

No effects of mitomycin-C in primary trabeculectomies in Sweden
por: Ayala, Marcelo
Publicado: (2018)

Trabeculectomy with double low dose of mitomycin C – two years of follow-up
por: Errico, Donato, et al.
Publicado: (2011)

Protective effects of hypercapnic acidosis on Ischemia–reperfusion-induced retinal injury
por: Lin, Le-Tien, et al.
Publicado: (2019)

Ologen implant versus mitomycin-C for trabeculectomy: A meta-analysis
por: Song, De-Sheng, et al.
Publicado: (2019)

Incidence of Postoperative Ptosis Following Trabeculectomy With Mitomycin C
por: Naruo-Tsuchisaka, Asako, et al.
Publicado: (2015)

Neovascularization of angle following trabeculectomy augmented with mitomycin-C
por: Shalaby, Wesam Shamseldin, et al.
Publicado: (2021)

Two routes of administration of mitomycin C in a trabeculectomy
por: Pillai, Manju, et al.
Publicado: (2023)

AR12286 Alleviates TGF-β-Related Myofibroblast Transdifferentiation and Reduces Fibrosis after Glaucoma Filtration Surgery
por: Cheng, Wen-Sheng, et al.
Publicado: (2020)

Effect of Mitomycin-C Augmented Trabeculectomy on Corneal Endothelial Cells
por: Zarei, Reza, et al.
Publicado: (2015)

Risk factors for choroidal detachment after trabeculectomy with mitomycin C
por: Haga, Akira, et al.
Publicado: (2013)

Evaluation of topical bevacizumab as an adjunct to mitomycin C augmented trabeculectomy
por: Zarei, Reza, et al.
Publicado: (2016)

Outcome of repeat trabeculectomy with mitomycin C in isolation or combined with phacoemulsification
por: Jagannathan, Jeevitha, et al.
Publicado: (2021)

Ologen implant versus mitomycin C in combined trabeculectomy and phacoemulsification
por: Paul, Chandrima, et al.
Publicado: (2022)

Toxic anterior segment syndrome following trabeculectomy with mitomycin C
por: Ginger-Eke, Helen, et al.
Publicado: (2023)

Collagen matrix vs mitomycin-C in trabeculectomy and combined phacoemulsification and trabeculectomy: a randomized controlled trial
por: Tanna, Angelo P., et al.
Publicado: (2016)

Exact matching of trabectome-mediated ab interno trabeculectomy to conventional trabeculectomy with mitomycin C followed for 2 years
por: Strzalkowska, A., et al.
Publicado: (2020)

Outcomes of Trabeculectomy With and Without Mitomycin C in Pseudoexfoliative Glaucoma Compared With Mitomycin C in Primary Open Angle Glaucoma
por: LOPES, Ana Sofia, et al.
Publicado: (2019)

Intravitreal bevacizumab with or without mitomycin C trabeculectomy in the treatment of neovascular glaucoma
por: Marey, Hatem M, et al.
Publicado: (2011)

Corneal lamellar grafting to repair late complications of mitomycin C trabeculectomy
por: Fukuchi, Takeo, et al.
Publicado: (2010)

The Influence of Phacoemulsification on Surgical Outcomes of Trabeculectomy with Mitomycin-C for Uveitic Glaucoma
por: Nishizawa, Asaho, et al.
Publicado: (2016)

Revision of trabeculectomy filtering blebs with mitomycin C: Long term results
por: Tulidowicz-Bielak, Maria, et al.
Publicado: (2016)

Simultaneous use of amniotic membrane and Mitomycin C in trabeculectomy for primary glaucoma
por: Yadava, Usha, et al.
Publicado: (2017)

Predictive Value of Bleb Vascularity after Mitomycin C Augmented Trabeculectomy
por: Wlaź, Aleksandra, et al.
Publicado: (2020)

Effect of oral statin use on mitomycin-C augmented trabeculectomy outcomes
por: Inobhas, Abhibol, et al.
Publicado: (2021)

A Modified Technique in Applying Sponge Soaked with Mitomycin C in Trabeculectomy
por: Zhang, Xiulan, et al.
Publicado: (2021)

Noncontact Conjunctiva: A Better Mitomycin C Application Site for Trabeculectomy
por: Liao, Yunru, et al.
Publicado: (2023)

Comparison of Surgical Outcomes between Trabeculectomy with Mitomycin C and Ahmed Valve Implantation with Mitomycin C in Eyes with Uveitic Glaucoma
por: Lee, Seung Yeop, et al.
Publicado: (2022)

Ocular decompression retinopathy after trabeculectomy with mitomycin-C for angle recession glaucoma
por: Bansal, Atul, et al.
Publicado: (2009)

A Comparative Study of Mitomycin C and 5-Fluorouracil Trabeculectomy in West Africa
por: Anand, Nitin, et al.
Publicado: (2012)

Subconjunctival bevacizumab to augment trabeculectomy with mitomycin C in the management of failed glaucoma surgery
por: Saeed, Ahmed M, et al.
Publicado: (2014)

The Effect of Adjuvant Intracameral Triamcinolone Acetonide on the Surgical Results of Trabeculectomy with Mitomycin C
por: Alagöz, Neşe, et al.
Publicado: (2016)

Comparison of outcomes of trabeculectomy with mitomycin C vs. ologen implant in primary glaucoma
por: Senthil, Sirisha, et al.
Publicado: (2013)

Fluctuation of intraocular pressure in glaucoma patients before and after trabeculectomy with mitomycin C
por: Wasielica-Poslednik, Joanna, et al.
Publicado: (2017)

The effectiveness of colchicine combined with mitomycin C to prolong bleb function in trabeculectomy in rabbits
por: Kokubun, Taiki, et al.
Publicado: (2019)

Scleral Flap Wound Dehiscence with Valsalva Maneuver After Trabeculectomy with Mitomycin C
por: Gungor, Sirel Gur, et al.
Publicado: (2022)

Does titration of mitomycin C as an adjunct to trabeculectomy significantly influence the intraocular pressure outcome?
por: Lee, Susan J, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_r2e7nb61cb0mbg5uj896vrfpjf