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Linking skeletal muscle aging with osteoporosis by lamin A/C deficiency

The nuclear lamina protein lamin A/C is a key component of the nuclear envelope. Mutations in the lamin A/C gene (LMNA) are identified in patients with various types of laminopathy-containing diseases, which have features of accelerated aging and osteoporosis. However, the underlying mechanisms for...

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Detalles Bibliográficos
Autores principales: Xiong, Lei, Zhao, Kai, Cao, Yu, Guo, Hao-Han, Pan, Jin-Xiu, Yang, Xiao, Ren, Xiao, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310860/
https://www.ncbi.nlm.nih.gov/pubmed/32479501
http://dx.doi.org/10.1371/journal.pbio.3000731