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Adaptive evolution among cytoplasmic piRNA proteins leads to decreased genomic auto-immunity
In metazoan germlines, the piRNA pathway acts as a genomic immune system, employing small RNA-mediated silencing to defend host DNA from the harmful effects of transposable elements (TEs). Expression of genomic TEs is proposed to initiate self regulation by increasing the production of repressive pi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310878/ https://www.ncbi.nlm.nih.gov/pubmed/32525870 http://dx.doi.org/10.1371/journal.pgen.1008861 |