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Persistence of HIV-1 Env-Specific Plasmablast Lineages in Plasma Cells after Vaccination in Humans

Induction of persistent HIV-1 Envelope (Env) specific antibody (Ab) is a primary goal of HIV vaccine strategies; however, it is unclear whether HIV Env immunization in humans induces bone marrow plasma cells, the presumed source of long-lived systemic Ab. To define the features of Env-specific plasm...

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Detalles Bibliográficos
Autores principales: Basu, Madhubanti, Piepenbrink, Michael S., Francois, Czestochowa, Roche, Fritzlaine, Zheng, Bo, Spencer, David A., Hessell, Ann J., Fucile, Christopher F., Rosenberg, Alexander F., Bunce, Catherine A., Liesveld, Jane, Keefer, Michael C., Kobie, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311075/
https://www.ncbi.nlm.nih.gov/pubmed/32577626
http://dx.doi.org/10.1016/j.xcrm.2020.100015