Piperine Alters the Pharmacokinetics and Anticoagulation of Warfarin in Rats

INTRODUCTION: Piperine, the bioactive compound of black pepper, and warfarin are metabolized by cytochrome P450 enzymes and are both highly plasma protein-bound compounds. In this study, we evaluated the effect of co-administered piperine on the pharmacokinetics and anticoagulation of warfarin in ra...

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Detalles Bibliográficos
Autores principales: Zayed, Aref, Babaresh, Wahby M, Darweesh, Ruba S, El-Elimat, Tamam, Hawamdeh, Sahar S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311098/
https://www.ncbi.nlm.nih.gov/pubmed/32607007
http://dx.doi.org/10.2147/JEP.S257919

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311098/
https://www.ncbi.nlm.nih.gov/pubmed/32607007
http://dx.doi.org/10.2147/JEP.S257919

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