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Piperine Alters the Pharmacokinetics and Anticoagulation of Warfarin in Rats

INTRODUCTION: Piperine, the bioactive compound of black pepper, and warfarin are metabolized by cytochrome P450 enzymes and are both highly plasma protein-bound compounds. In this study, we evaluated the effect of co-administered piperine on the pharmacokinetics and anticoagulation of warfarin in ra...

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Detalles Bibliográficos
Autores principales:	Zayed, Aref, Babaresh, Wahby M, Darweesh, Ruba S, El-Elimat, Tamam, Hawamdeh, Sahar S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311098/ https://www.ncbi.nlm.nih.gov/pubmed/32607007 http://dx.doi.org/10.2147/JEP.S257919

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