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Mechanisms of chromosome biorientation and bipolar spindle assembly analyzed by computational modeling

The essential functions required for mitotic spindle assembly and chromosome biorientation and segregation are not fully understood, despite extensive study. To illuminate the combinations of ingredients most important to align and segregate chromosomes and simultaneously assemble a bipolar spindle,...

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Detalles Bibliográficos
Autores principales: Edelmaier, Christopher, Lamson, Adam R, Gergely, Zachary R, Ansari, Saad, Blackwell, Robert, McIntosh, J Richard, Glaser, Matthew A, Betterton, Meredith D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311174/
https://www.ncbi.nlm.nih.gov/pubmed/32053104
http://dx.doi.org/10.7554/eLife.48787