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Drug Antagonism and Single Agent Dominance Result from Differences in Death Kinetics

Cancer treatment generally involves drugs used in combinations. Most prior work has focused on identifying and understanding synergistic drug-drug interactions; however, understanding antagonistic interactions remains an important and understudied issue. To enrich for antagonism and reveal common fe...

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Detalles Bibliográficos
Autores principales: Richards, Ryan, Schwartz, Hannah R., Honeywell, Megan E., Stewart, Mariah S., Cruz-Gordillo, Peter, Joyce, Anna J., Landry, Benjamin D., Lee, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311243/
https://www.ncbi.nlm.nih.gov/pubmed/32251407
http://dx.doi.org/10.1038/s41589-020-0510-4