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High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy

Microbial diversity in the cystic fibrosis (CF) lung decreases over decades as pathogenic bacteria such as Pseudomonas aeruginosa take over. The dynamics of the CF microbiome and metabolome over shorter time frames, however, remain poorly studied. Here, we analyze paired microbiome and metabolome da...

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Detalles Bibliográficos
Autores principales: Raghuvanshi, Ruma, Vasco, Karla, Vázquez-Baeza, Yoshiki, Jiang, Lingjing, Morton, James T., Li, Danxun, Gonzalez, Antonio, DeRight Goldasich, Lindsay, Humphrey, Gregory, Ackermann, Gail, Swafford, Austin D., Conrad, Douglas, Knight, Rob, Dorrestein, Pieter C., Quinn, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311317/
https://www.ncbi.nlm.nih.gov/pubmed/32576651
http://dx.doi.org/10.1128/mSystems.00292-20