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Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation

Thymic stromal lymphopoietin (TSLP) is a critical upstream cytokine inducing type 2 inflammation in various diseases, including asthma and atopic dermatitis. Accumulating evidence suggests that TSLP can directly stimulate a variety of immune cells, such as dendritic cells (DCs), basophils, T cells,...

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Detalles Bibliográficos
Autores principales: Kabata, Hiroki, Flamar, Anne-Laure, Mahlakõiv, Tanel, Moriyama, Saya, Rodewald, Hans-Reimer, Ziegler, Steven F., Artis, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311324/
https://www.ncbi.nlm.nih.gov/pubmed/32066836
http://dx.doi.org/10.1038/s41385-020-0266-x