Cargando…
Targeted deletion of the TSLP receptor reveals cellular mechanisms that promote type 2 airway inflammation
Thymic stromal lymphopoietin (TSLP) is a critical upstream cytokine inducing type 2 inflammation in various diseases, including asthma and atopic dermatitis. Accumulating evidence suggests that TSLP can directly stimulate a variety of immune cells, such as dendritic cells (DCs), basophils, T cells,...
Autores principales: | Kabata, Hiroki, Flamar, Anne-Laure, Mahlakõiv, Tanel, Moriyama, Saya, Rodewald, Hans-Reimer, Ziegler, Steven F., Artis, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311324/ https://www.ncbi.nlm.nih.gov/pubmed/32066836 http://dx.doi.org/10.1038/s41385-020-0266-x |
Ejemplares similares
-
The neuropeptide Neuromedin U stimulates innate lymphoid cells and type 2 inflammation
por: Klose, Christoph S.N., et al.
Publicado: (2017) -
Central Role of Cellular Senescence in TSLP-Induced Airway Remodeling in Asthma
por: Wu, Jinxiang, et al.
Publicado: (2013) -
TSLP calms inflammation
por: Maxmen, Amy
Publicado: (2009) -
TSLP regulates intestinal immunity and inflammation in mouse models of helminth infection and colitis
por: Taylor, Betsy C., et al.
Publicado: (2009) -
Airway epithelial TSLP production of TLR2 drives type 2 immunity in allergic airway inflammation
por: Lv, Jiajia, et al.
Publicado: (2018)