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CD47 is a negative regulator of intestinal epithelial cell self-renewal following DSS-induced experimental colitis

CD47 deficient mice are resistant to dextran sulfate sodium (DSS)-induced experimental colitis. The underlying mechanism, however, remains incompletely understood. In this study, we characterized the role of CD47 in modulating homeostasis of gastrointestinal tract. We found that CD47 expression in b...

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Detalles Bibliográficos
Autores principales: He, Yueqin, Sun, Xinlei, Rong, Weiwei, Yang, Rong, Liang, Hongwei, Qi, Ying, Li, Limin, Zen, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311394/
https://www.ncbi.nlm.nih.gov/pubmed/32576895
http://dx.doi.org/10.1038/s41598-020-67152-w