Monosialoganglioside GM1 reduces toxicity of Ptx and increase anti-metastasic effect in a murine mammary cancer model

Having demonstrated the ability of monosialoganglioside GM1 micelles as oncology drug transporter, this work focuses on evaluating its application in an in vivo system, studying the toxicity and antitumoral effect of GM1-Ptx micellar formulation. The maximum tolerated dose (MTD) obtained after intra...

Descripción completa

Detalles Bibliográficos
Autores principales: Leonhard, Victoria, Alasino, Roxana V., Pasqualini, María E., Cremonezzi, David C., García, Néstor H., Beltramo, Dante M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311431/
https://www.ncbi.nlm.nih.gov/pubmed/32576898
http://dx.doi.org/10.1038/s41598-020-67256-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311431/
https://www.ncbi.nlm.nih.gov/pubmed/32576898
http://dx.doi.org/10.1038/s41598-020-67256-3

Ejemplares similares