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Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage

Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA acc...

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Detalles Bibliográficos
Autores principales: Digiovanni, Stefania, Visentin, Cristina, Degani, Genny, Barbiroli, Alberto, Chiara, Matteo, Regazzoni, Luca, Di Pisa, Flavio, Borchert, Andrew J., Downs, Diana M., Ricagno, Stefano, Vanoni, Maria Antonietta, Popolo, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311433/
https://www.ncbi.nlm.nih.gov/pubmed/32576850
http://dx.doi.org/10.1038/s41598-020-66663-w