Cargando…
Two novel fish paralogs provide insights into the Rid family of imine deaminases active in pre-empting enamine/imine metabolic damage
Reactive Intermediate Deaminase (Rid) protein superfamily includes eight families among which the RidA is conserved in all domains of life. RidA proteins accelerate the deamination of the reactive 2-aminoacrylate (2AA), an enamine produced by some pyridoxal phosphate (PLP)-dependent enzymes. 2AA acc...
Autores principales: | Digiovanni, Stefania, Visentin, Cristina, Degani, Genny, Barbiroli, Alberto, Chiara, Matteo, Regazzoni, Luca, Di Pisa, Flavio, Borchert, Andrew J., Downs, Diana M., Ricagno, Stefano, Vanoni, Maria Antonietta, Popolo, Laura |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311433/ https://www.ncbi.nlm.nih.gov/pubmed/32576850 http://dx.doi.org/10.1038/s41598-020-66663-w |
Ejemplares similares
-
Imine Deaminase Activity and Conformational Stability of UK114, the Mammalian Member of the Rid Protein Family Active in Amino Acid Metabolism
por: Degani, Genny, et al.
Publicado: (2018) -
Differentiation between enamines and tautomerizable imines in the oxidation reaction with TEMPO
por: Jie, Xiaoming, et al.
Publicado: (2018) -
Members of the Rid protein family have broad imine deaminase activity and can accelerate the Pseudomonas aeruginosa D-arginine dehydrogenase (DauA) reaction in vitro
por: Hodge-Hanson, Kelsey M., et al.
Publicado: (2017) -
Construction of highly-stable covalent organic framework with combined enol-imine and keto-enamine linkages
por: Jiang, Jian, et al.
Publicado: (2023) -
Evidence for a Negative Correlation between Human Reactive Enamine-Imine Intermediate Deaminase A (RIDA) Activity and Cell Proliferation Rate: Role of Lysine Succinylation of RIDA
por: Siculella, Luisa, et al.
Publicado: (2021)